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The Pediatric Clinics of North America: New Frontiers in Pediatric Drug Therapy

Benoit Bailey MD and Gideon Koren MD, guest editors. Vol. 44, No. 1, Feb. 1997. W.B. Saunders Company, a division of Harcourt Brace & Company

Series of articles on new trends and methodologies in pediatric pharmacology. This 264-page issue of the bi-monthly Pediatric Clinics of North America, highlights recent advances in drug therapy in children, gene and fetal therapy and pharmacogenetics. This volume also includes thoughtful articles on the ethical boundaries of drug research in pediatrics, ways to assess drug compliance and implement effective compliance strategies, breastfeeding and maternal drug use, and more.

Order direct from W.B. Saunders Co. :

Within North America (NA) : 1-800-654-2452
From outside NA : 1-407-345-4000

Contents:

Preface



xiii

Drug Compliance in Pediatrics: Clinical and Research Issues
Doreen M. Matsui
1
Noninvasive Methods for Drug Measurement in Pediatrics
Benoit Bailey, Julia Klein and Gideon Koren
15
Ethical Boundaries of Drug Research in Pediatrics
Mary Rowell and Stanley Zlotkin
27
Breast-Feeding and Maternal Drug Use
Benoit Bailey and Shinya Ito
41
Pharmacogenetics in Pediatrics: Implications for Practice
J. Steven Leeder and Gregory L. Kearns
55
Adverse Drug Reactions from Birth to Early Childhood
Abhya Gupta and Lisa K. Waldhauser
79
In Vivo and In Vitro Testing for Adverse Drug Reactions
Michael J. Rieder
93
Fetal Drug Therapy
Adam A. Rosenberg and Henry L .Galan
113
Control of Cerebral and Ocular Blood Flow Autoregulation in Neonates
Pierre Hardy, Daya R. Varma, and Sylvain Chemtob
137
Genetic Therapy: Past, Present and Future
Terence R. Flotte and Thomas W. Ferkol
153
Advances in the Therapy for Sepsis in Children
Michael R. Anderson and Jeffrey L. Blumer
179
Pharmacology of Pediatric Resuscitation
H. Michael Ushay and Daniel A. Notterman
207
Oral Iron Chelation with Deferiprone
Orna Diav-Citrin and Gideon Koren
235
Recent Advances in the Treatment of Bronchiolitis and Laryngitis
Terry P. Klassen
249
index 263
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