• Home
  • Pregnancy &           
  • Bookshop
  • Contact us
  • Donate now
  • Frequently Asked Questions
  • Please read

Our Helplines

1-877-439-2744 Motherisk Helpline
1-800-436-8477 Morning Sickness
1-877-327-4636 Alcohol and Substance
1-866-937-7678 Exercise in Pregnancy
1-888-246-5840 HIV and HIV Treatment
416-813-6780 Motherisk Helpline

Motherisk Book List

Retinoids in Clinical Practice ; The Risk-Benefit Ratio

(G. Koren, Ed). Marcel Dekker, NY 1993.

edited by Gideon Koren. Marcel Dekker, Inc. 1993.

A review of the elements involved in the risk-benefit ratio of retinoids, a unique and potent group of pharmacological agents. Written to help clinicians, ethicists, scientists, the pharmaceutical industry and regulatory agencies understand the complexities underlying the risk-benefit ratio of unique but highly teratogenic drugs.

To order, click here.


1. Therapeutic Efficacy of Retinoids
J.A.J. Kovacs and Neil H. Shear
2. Vitamin A in the Fetus and Newborn
Rafael Gorodischer
3. Developmental Toxicology of Retinoids
Narsingh D. Agnish and Devendra M. Kochhar
4. Retinoid Embryopathy in Humans
Franz W. Rosa
5. Neural and Behavioral Pathology Following PrenatalExposure to Retinoids
Jane Adams
6. Clinical Relevance of Retinoid Parmacokinetics
Julia Klein, Anne L. Pastuszak and Gideon Koren
7. The Retinoid Pregnancy Prevention Program
Anne L . Pastuszak and Gideon Koren
8. Analysis of Contraception Failure in Canadian Women Treated with Systemic Retinoids
Anne L. Pastuszak and Gideon Koren
9. A New Approach to Counseling Women on Their Teratogenic Risk
Gideon Koren
10. Retinoid Embryopathy: Epidemiological Perspectives
Donald L. Kaiser
11. Regulatory Evolution: Approach to the Marketing of a Known Teratogen, Isotretinoin (Accutane)
Michèle Brill-Edwards and Celia Viets
12. Adverse Nonreproductive Effects of Retinoids in Humans
J.A.J. Kovacs and Neil H. Shear
13. Isotretinoin Benefits and Risks: Assessment of the Ratio
Gideon Koren
index 267
Valid XHTML 1.0 Transitional [Valid RSS]

Motherisk is proud to be affiliated with OTIS, The Organization of Teratology Information Specialists. OTIS is a network of information services across North America.

* - "MOTHERISK - Treating the mother - Protecting the unborn" is an official mark of The Hospital for Sick Children. All rights reserved.

The information on this website is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and before you take any medications.

Copyright © 1999-2015 The Hospital for Sick Children (SickKids). All rights reserved.

The Hospital for Sick Children (SickKids) is a health-care, teaching and research centre dedicated exclusively to children; affiliated with the University of Toronto. For general inquires please call: 416-813-1500.

  |  Contact SickKids  |  Terms of Use