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Motherisk News: Babies can be exposed to "crystal meth" while in the womb

Methamphetamine detection in maternal and neonatal hair: mplications for safety
Online First: Arch Dis Child Fetal Neonatal Edition 2006; doi: 10.1136/adc.2006.100156

Babies can be exposed to methamphetamine or ?crystal meth? while in the womb, reveals an analysis of hair samples, published ahead of print in the Fetal and Neonatal Edition of Archives of Disease in Childhood.

Blood and urine samples, the most commonly used detection methods, are not capable of registering cumulative effects, because they reflect only very recent use, and they cannot always distinguish among different drugs, say the authors.

Crystal meth, also known as Krank, Tina, or Tweak, is snorted, injected, or smoked. It boosts alertness and promotes a sense of wellbeing, euphoria, and exhilaration. It also curbs appetite and enhances sexual arousal.

But long term abuse damages nerves in the brain and can lead to psychotic behaviour and aggression.

The drug is very easy to manufacture in home laboratories, and global use has soared, particularly among young women, say the authors. An estimated half a million Americans alone are thought to use it every week, including 5% of pregnant women.

The authors carried out hair sample analysis on more than 8,000 people, totalling more than 34,000 test results between 1997 and 2005.

In all, 396 samples tested positive for crystal meth, accounting for 8% of the total during this period. This number included 11 mother and baby pairs.

All but 14 of the samples testing positive for crystal meth had been sent for analysis in 2005. The first positive cases dated from 2003.

Wide ranging levels of the drug were found in both the mothers? and the newborns? hair samples, but the levels matched, indicating that the drug is able to cross the placenta directly to the developing fetus, say the authors.

Only one newborn had no evidence of the drug in its hair.

Crystal meth users seem more likely to use other illegal drugs, the findings show.

Most (85%) of the 396 samples testing positive for crystal meth also tested positive for at least one other illegal drug, predominantly cocaine. Evidence of other drugs was found in 38% of samples testing negative for crystal meth.

Bleaching or straightening the hair will not erase the chemical evidence it holds, say the authors, and because hair only starts to grow on a developing fetus at around 20 weeks, the mother will have known about her pregnancy for several months.

Drug abuse boosts the chances of complications of pregnancy and triples the likelihood of serious medical problems among the babies born.

The authors say that the precise effects of crystal meth on a fetus are not fully known, but the evidence to date points to restricted fetal growth and developmental problems

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The information on this website is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and before you take any medications.

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