Vitamin A and Congeners

Motherisk Research

• Lancet. 350(9085):1143-4, 1997 Oct 18.
  Shapiro L, Pastuszak A, Curto G, Koren G: Safety of first-trimester exposure to topical tretinoin: prospective cohort study [letter].
• Ther Drug Monitor 14: 197-202, 1992.
  Klein J, Fernandes D, Pastuszak A, Koren, G: Therapeutic drug monitoring of retinoids.
• Koren G: Embryopathy associated with retinoic acid. N Engl J Med 315:262, 1986.
  
• Reprod Toxicol 8: 63-68, 1994.
  Pastuszak AL, Koren G, Rieder MJ: Use of retinoid pregnancy prevention program in Canada: Patterns of contraception use in women treated with the systemic retinoids isotretinoin and etretinate.
• Can Fam Physician 43: 216-219, 1997.
  Koren G, Pastuszak A: How to ensure fetal safety when mothers use isotretinoine (Accutane).
• http://www.pulsus.com/journals/abstract.jsp?jnlKy=9&atlKy=2176&isuKy=608&isArt=t&HCtype=Consumer
  Pastuszak A, Burke B, Koren G: When potent teratogens are irreplaceable drugs: Lessons of thalidomide and isotretinoin. Can J Clin Pharmacol 4/2 (67-73) 1997.
• CMAJ. 1999 Jun 15;160(12):1719-20. No abstract available.
  Atanackovic G, Koren G: Fetal exposure to oral isotretinoin: failure to comply with the Pregnancy Prevention Program.
• J Clin Pharmacol. 1998 Oct;38(10):926-30.
  Nulman I, Berkovitch M, Klein J, Pastuszak A, Lester RS, Shear N, Koren G: Steady-state pharmacokinetics of isotretinoin and its 4-oxo metabolite: implications for fetal safety.