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The Cancer in Pregnancy Forum

Archived Questions and Answers
This Forum has been the centre of an exceptional exchange of knowledge diagnosis, treatment, symptoms and other effects of cancer during pregnancy and lactation. All are welcome to review the Questions and Answers posted here, provided that they acknowledge and accept the important proviso and disclaimer below.
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Forum > Chemotherapy: Paternal
6 Mercaptopurine taken by male

CCoPE
Date: 2003-11-11

Question:
My husband is taking Mercaptopurine, Petizone and Asacol to control his Ulcertative Colitis. We have been trying to get pregnant for the past year and have recently read that Mercaptopurine (even if taken by the father) can cause serious birth defects in the fetus. Is this more common if he is on the drug for prolonged periods of time (it has only been 1 month that he has been taking it)? Are birth defects common to parents taking this drug? What are the other risks? Should we stop "trying"? What if I am already pregnant? Thanks for your help.

Answer:
The following information should not replace the assessment and advice you have been receiving from your physician (cancer specialist, obstetrician, or any other healthcare provider). It is offered for your information only

The info given to you is not correct. 6 mercaptopurine when taken by the male, has not been shown to increase malformation rates.

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