• Home
  • Pregnancy &           
Breastfeeding
  • Bookshop
  • Contact us
  • Donate now
  • Frequently Asked Questions
  • Please read

Our Helplines

1-877-439-2744 Motherisk Helpline
1-800-436-8477 Morning Sickness
1-877-327-4636 Alcohol and Substance
1-866-937-7678 Exercise in Pregnancy
1-888-246-5840 HIV and HIV Treatment
416-813-6780 Motherisk Helpline

The Cancer in Pregnancy Forum

Archived Questions and Answers
This Forum has been the centre of an exceptional exchange of knowledge diagnosis, treatment, symptoms and other effects of cancer during pregnancy and lactation. All are welcome to review the Questions and Answers posted here, provided that they acknowledge and accept the important proviso and disclaimer below.
Submit a question
Forum > Chemotherapy: Maternal
Effects of chemo before pregnancy and within first trimester

CCoPE
Date: 2004-01-03

Question:
29 yo lady treated for Acute Promyelocytic Leukemia with Idaubicin and ATRA between the period of Jan to Oct/03. Last chemotherapy received Oct 12/03 where she completed 6 monthly doses of Idarubicin and ATRA (all transretinoic acid). Now pregnant of 6 wks. We were planning to put her on maintenance of oral 6-MP and methotrexate prior to her getting pregnant. What would your advise be? What would the consequences be having been exposed to the above chemotherapy 1-2 months before getting pregnant? Thank you

Answer:
Exposure to the medications in question, or any other human chemotherapy, 2 to 3 months before conception has not been associated with malformations. If the maintenance with 6MP and MTX is deemed clinically important, they should be avoided in the first trimester.

Valid XHTML 1.0 Transitional [Valid RSS]

* - "MOTHERISK - Treating the mother - Protecting the unborn" is an official mark of The Hospital for Sick Children. All rights reserved.

The information on this website is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and before you take any medications.

Copyright © 1999-2013 The Hospital for Sick Children (SickKids). All rights reserved.

The Hospital for Sick Children (SickKids) is a health-care, teaching and research centre dedicated exclusively to children; affiliated with the University of Toronto. For general inquires please call: 416-813-1500.

  |  Contact SickKids  |  Terms of Use