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Current Studies at Motherisk
The Safety of Diclectin in Breastfeeding
Neurodevelopment of Children Exposed in-Utero to Chemotherapy for Maternal Breast Cancer (Dr. I Nulman)
Diclegis Surveillance Program Study
Diclectin Surveillance Program Study
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Alcohol Use during Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
The Motherisk Nausea and Vomiting of Pregnancy (NVP) ForumMotherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.
I have tried Diclectin to combat "morning sickness" which was impairing my ability to work; unfortunately it made me excessively sleepy, disoriented and stupid, and thus didn't solve the problem. I understand Vitamin B6 supplements can help as an alternative; if so, how much B6 should I take, and how often, to combat nausea (which is in my case prevalent first thing in the morning but present throughout the day)?
Doxylamine succinate (the antihistamine in Diclectin), can cause some drowsiness for some women, although most get used to this side effect after a while. Dosing may also be a factor.
Vitamin B6 can be taken as a supplement. We usually suggest 25 mg once, twice or three times a day. The safety of this amount has been addressed by a Motherisk study of women taking up to 8 Diclectin pills per day (e.g, 80 mg of Vitamin B6). The study showed no increase in the percentage of birth defects over the 1 percent to 3 percent baseline risk that is present in any pregnancy.
Call our Motherisk NVP Helpline at 1-800-436-8477 for more information.