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The Motherisk Nausea and Vomiting of Pregnancy (NVP) Forum

Motherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.

Kytril in pregnancy

NVP Counselor
Date: 2004-11-08

Question:
what is your opinion about taking Kytril for NVP. what does the research show and a general recommendation.

Answer:
There is no information on Kytril in pregnancy. However, it is in the same group of drugs as ondansetron (Zofran). The Motherisk study on Zofran was published in the September issue of the British Journal of Obstetrics and Gynecology. Out of 176 women on Zofran who were followed up after they gave birth, 6 had babies with birth defects (3 of which were hypospadias - a very common defect present in 1 out of 300 male babies). This falls within the 1 to 3 percent baseline risk for malformation that is present in any pregnancy.

Please view our treatment algorithm for more information, consult your physician, and/or speak to a teratogen information counselor. If you are in the US, visit the OTIS website for a teratogen information service in your area.

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