1-877-327-4636 Alcohol and Substance
1-800-436-8477 Morning Sickness
1-888-246-5840 HIV and HIV Treatment
1-877-439-2744 Motherisk Helpline
416-813-6780 Motherisk Helpline
Pregnancy & Breastfeeding Resources
- Read more in our News Archive
Current Studies at Motherisk
Neurodevelopment of Children Exposed in-Utero to Chemotherapy for Maternal Breast Cancer (Dr. I Nulman)
Diclegis Surveillance Program Study
Diclectin Surveillance Program Study
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Environmental Exposures and Children's Health
Alcohol Use during Pregnancy
Control of Hypertension in Pregnancy Study
Folic Acid Before and During Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
The Motherisk Nausea and Vomiting of Pregnancy (NVP) ForumMotherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.
In my last pregnancy I took the maximum dose of dicletin ( 1am, 1lunch and 2 hs) I still vomited several times a day, and was sick for about 6 months. I would like to know if long term use of gravol is safe. I think I might be pregnant and I would like to take gravol asap and for the duration of my n/v. My doctor is cautious and does not approve of gravol, I only gained 10 lbs with my son and he was a low birth weight baby. I don't want to harm the baby but I just can't go through that again.
The dose of Diclectin that you mentioned is the indicated dose in the product monograph that your physician would have consulted. However Motherisk published a study where women had taken up to 8 tablets/day with no adverse effects on the baby. Talk to your doctor and when you do, you may want to refer him or her to this research: Atanackovic G, Navioz Y, Moretti ME, Koren G: The safety of higher than standard dose of doxylamine-pyridoxine (Diclectin) for nausea and vomiting of pregnancy. J Clin Pharmacol 2001 Aug;41(8):842-5
Gravol is an antihistamine similar to one of the drugs found in Diclectin and is safe to use, but it would probably be no more effective than Diclectin, especially since it does not contain Vitamin B6 which is in Diclectin.