1-877-327-4636 Alcohol and Substance
1-800-436-8477 Morning Sickness
1-888-246-5840 HIV and HIV Treatment
1-877-439-2744 Motherisk Helpline
416-813-6780 Motherisk Helpline
Pregnancy & Breastfeeding Resources
Current Studies at Motherisk
The Safety of Diclectin in Breastfeeding
Neurodevelopment of Children Exposed in-Utero to Chemotherapy for Maternal Breast Cancer (Dr. I Nulman)
Diclegis Surveillance Program Study
Diclectin Surveillance Program Study
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Alcohol Use during Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
The Motherisk Nausea and Vomiting of Pregnancy (NVP) ForumMotherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.
Thank you so much for the information about diclectin, doxylamine succinate, and the use of Unisom and vitamin B6. It has made a world of difference for me! I was hoping it would work, but I never dreamed it would work this well. I cannot thank everyone enough at Motherisk for relieving my pain and suffering.
We are delighted to hear that the advice you received from our NVP Helpline was helpful. We repeat it here for the benefit of other women also suffering from NVP. The drug of choice in Canada is Diclectin. It contains 10 mg of Vitamin B6 and 10 mg of doxylamine succinate in each delayed release tablet. These two substances are known to be safe for use during pregnancy and not to increase the 1% to 3% baseline risk for birth defects present in each pregnancy. In the U.S., Diclectin is not yet available but its two components are available over the counter. Therefore, although it is not the same as taking 4 delayed-release tablets of Diclectin per day, some physicians in the US are recommending that their patients try a prescribed combination of Unisom and Vitamin B6. Talk to your doctor and see what he or she recommends.