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The Motherisk Nausea and Vomiting of Pregnancy (NVP) Forum

Motherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.

Forum > Treatment: Diclectin
Does Diclectin increase the baseline risk of malformation?

Date: 2001-01-16

My wife is suffering from NVP and I was wondering if you have any current information on the drug "Diclectin" which her doctor prescribed two days ago. We have not started taking the drug because I want to first do a little research first. I've looked through your web site "http://www.motherisk.org" and have found little information detailing the tests performed on the drug and its side effects. Most of the information that I found deals with doctors saying that the drug is safe (but I would like to know why they think it is so safe). Also, most of the information listed at your web site dates back to 1998 and later. Note: My wife is within her 15th - 16th week of pregnancy. The doctor also mentioned that we are quickly approaching the point where we need to take action (ie. the drug Diclectin). Since my wife keeps vomiting almost every time within 20 minutes of eating she and the baby are not getting enough nutrition. Reason why I?m reluctant in having her take any drugs while she?s pregnant is due to the fact that while my mom was pregnant with my sister a doctor prescribed a drug to ease the effects of NVP. To make a long story short... there were side effects and my sister is now almost blind. Please let me know where I can find more information on "Diclectin" so that I will feel better about letting her take this drug.

For more information on NVP, Diclectin and its use, please call our Motherisk Helpline at 1-800-436-8477. You can discuss your concerns in depth with a Motherisk NVP counsellor.

To reassure you quickly, however, if your wife needs help rapidly, Diclectin, previously known as Bendectin, has been used for the treatment of NVP for 40 years and over 20 studies have confirmed that the 2 substances contained in the medication, (Vitamin B6 and doxylamine succinate), do not increase the 1% to 3% baseline risk of major malformation that is present in all pregnancies.

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