National sponsor of the Motherisk Program
Our Helplines
1-877-327-4636 Alcohol and Substance
1-800-436-8477 Morning Sickness
1-888-246-5840 HIV and HIV Treatment
1-877-439-2744 Motherisk Helpline
416-813-6780 Motherisk Helpline
Pregnancy & Breastfeeding Resources
Current Studies at Motherisk
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Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
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Pregnancy in Women with Multiple Sclerosis
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Environmental Exposures and Children's Health
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Alcohol Use during Pregnancy
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Control of Hypertension in Pregnancy Study
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Folic Acid Before and During Pregnancy
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Lamisil in Pregnancy
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Meridia in Pregnancy
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Autoimmune Diseases in Pregnancy Project
The Motherisk Nausea and Vomiting of Pregnancy (NVP) Forum
Motherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.
Treatment
Date: 2001-03-27
Question:
Is the drug zofran safe to use in pregnancy for vomiting?
Answer:
The numerous questions to our NVP Helpline and this NVP Forum about Zofran as a medication for NVP and HG, its frequent reported use (especially in the US), as well as the limited safety information on its use, have prompted Motherisk to conduct a safety study. Pregnant women taking Zofran are invited to call our toll-free Helpline at 1-800-436-8477 to take part in this study.
To date, three case reports have been published, with no adverse effects. One prospective study of 15 women also reported no difference in birth outcome.
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