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Our Helplines

Motherisk Helpline
1-877-439-2744 (Toll-free)
416-813-6780 (Toronto and GTA)

Alcohol and Substance

Fluconazole use during breastfeeding

I have a patient with persistent breast and nipple thrush. Other therapies have failed, so I have decided to treat her with a loading dose of 400 mg of oral fluconazole followed by 100 mg twice daily for at least 2 weeks.

Is there any need for her to interrupt breastfeeding during this treatment? more »

Safety of tacrolimus in pregnancy

I have a 30-year-old patient who had a kidney transplant 2 years ago. She is now planning a pregnancy. She has been treated with tacrolimus since her transplant. Will it be safe for the fetus if she continues to take it during the pregnancy or should she switch to a different antirejection medication?

learn more »»

Motherisk Helplines

The Motherisk Program at The Hospital for Sick Children is a teratogen information service providing up-to-date information about the risk and safety of medications and other exposures during pregnancy and breastfeeding. Research and education in the program is also an important ongoing activity.

Motherisk counselors are ready to answer calls and provide information to women, their partners and health-care providers.

Motherisk Helpline
Provides evidence-based information about the risk or safety of prescription and over-the-counter medications, herbal products, chemicals, radiation, chronic diseases, infections, occupational, environmental, and other exposures during pregnancy and while breastfeeding.

Monday to Friday 9 a.m. to noon and 1 to 5 p.m. eastern standard time.

Alcohol and Substance Use Helpline 1-877-327-4636
Provides information about the safety or risk of alcohol, nicotine and recreational drugs such as marijuana, cocaine and ecstasy during pregnancy and breastfeeding.

Monday to Friday 9 a.m. to noon and 1 to 5 p.m. eastern standard time.

Motherisk Clinic

Planning and pregnant women come to the Motherisk Clinic in Toronto following exposure to known or suspected teratogens (substances that cause abnormalities in the developing fetus), new and unfamiliar drugs, chronic drug therapy or drugs of abuse. Clinic visits are by appointment only. Call 1-877-439-2744 or 416-813-6780 or your health care provider can send a referral by visiting http://www.sickkids.ca/ambulatoryclinics.

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Motherisk is a proud affiliate of MotherToBaby, an information service of the non-profit Organization of Teratology Information Specialists (OTIS) across North America.

* - "MOTHERISK - Treating the mother - Protecting the unborn" is an official mark of The Hospital for Sick Children. All rights reserved.

The information on this website is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and before you take any medications.

Copyright © 1999-2018 The Hospital for Sick Children (SickKids). All rights reserved.

The Hospital for Sick Children (SickKids) is a health-care, teaching and research centre dedicated exclusively to children; affiliated with the University of Toronto. For general inquires please call: 416-813-1500.

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